My gastroenterologist has tried just about everything for me, and not much works real well. I only got through our recent trip to London thanks to massive doses of Prednisone and lots and lots of over-the-counter anti-diarrhea medicine. Then they came out with Cimzia. Cimzia is essentially the same molecule as Remicade, but it is (A) completely laboratory manufactured -- no mice at all and (B) administered very differently. I gave myself two shots every four weeks with the fancy-schmancy ergonomic pre-filled needles shown up above. The hope was that I was reacting to the mouse origins. We tried this for about six months.
Six months, by the way, was how long it took for me to react badly to Remicade. And, like magic, my six-month doses of Cimzia caused a reaction too. A pretty awful one; the neuropathy pain started at the injection sites about an hour afterwards, and spread to both arms and both legs. The bottom line is that it wasn't the mice, it was the molecule itself, and my latest experiment in Crohn's treatment was not only unsuccessful, but spectacularly so. And I seem to have done myself increased damage in the process.
The only treatment I haven't tried -- because I don't live anywhere near where it's offered -- is to deliberately infect myself with a form of parasitic worm normally found in pigs. The idea is that autoimmune diseases are caused when the body attacks itself because there's nothing else for them to attack. It's actually a "thing;" Hugh Laurie even used it on "House, M.D."
And so the adventure continues....